Carmelo Rizzari Selected Research

Asparaginase (Elspar)

1/2022	Pre-existing antibodies against polyethylene glycol reduce asparaginase activities on first administration of pegylated E. coli asparaginase in children with acute lymphocytic leukemia.
1/2022	Pharmacological and clinical monitoring in children with acute lymphoblastic leukemia treated with a biogeneric PEG-l-asparaginase product.
12/2021	ALL blasts drive primary mesenchymal stromal cells to increase asparagine availability during asparaginase treatment.
10/2021	Can recombinant technology address asparaginase Erwinia chrysanthemi shortages?
1/2020	Therapeutic Drug Monitoring of Asparaginase: Intra-individual Variability and Predictivity in Children With Acute Lymphoblastic Leukemia Treated With PEG-Asparaginase in the AIEOP-BFM Acute Lymphoblastic Leukemia 2009 Study.
1/2020	Increasing completion of asparaginase treatment in childhood acute lymphoblastic leukaemia (ALL): summary of an expert panel discussion.
1/2019	Asparagine levels in the cerebrospinal fluid of children with acute lymphoblastic leukemia treated with pegylated-asparaginase in the induction phase of the AIEOP-BFM ALL 2009 study.
6/2017	Pharmacodynamic effects in the cerebrospinal fluid of rats after intravenous administration of different asparaginase formulations.
3/2016	Consensus expert recommendations for identification and management of asparaginase hypersensitivity and silent inactivation.
2/2016	Early T-cell precursor acute lymphoblastic leukaemia in children treated in AIEOP centres with AIEOP-BFM protocols: a retrospective analysis.

For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Carmelo Rizzari Research Topics

Disease

29	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/2022 - 07/2002
8	Hypersensitivity (Allergy) 03/2022 - 01/2006
7	Residual Neoplasm 05/2022 - 03/2014
6	Leukemia 01/2019 - 09/2005
4	Philadelphia Chromosome 01/2021 - 07/2013
4	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 01/2021 - 07/2013
4	Neoplasms (Cancer) 12/2020 - 07/2013
3	Headache (Headaches) 01/2021 - 07/2013
3	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 10/2020 - 02/2013
3	Infections 01/2020 - 05/2007
2	Disease Progression 01/2022 - 01/2019
2	Hemophagocytic Lymphohistiocytosis (Hemophagocytic Syndrome) 01/2022 - 01/2020
2	Fever (Fevers) 01/2021 - 10/2019
2	COVID-19 12/2020 - 01/2020
2	Vomiting 01/2020 - 07/2013
2	Hematologic Neoplasms (Hematological Malignancy) 01/2019 - 06/2017
1	Mucopolysaccharidoses 01/2022
1	Exanthema (Rash) 01/2020
1	Histoplasmosis 01/2020
1	Hypertension (High Blood Pressure) 01/2020
1	Obesity 01/2020
1	Pancreatitis 01/2020
1	Thrombosis (Thrombus) 01/2020
1	Human Influenza (Influenza) 10/2019
1	Aneuploidy (Aneuploid) 08/2019
1	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL) 01/2016
1	Communicable Diseases (Infectious Diseases) 12/2014
1	Familial Exudative Vitreoretinopathies 12/2013
1	Norrie disease 12/2013
1	Diarrhea 07/2013
1	Nausea 07/2013
1	Venous Thrombosis (Deep-Vein Thrombosis) 07/2013
1	Burkitt Lymphoma (Burkitt's Lymphoma) 06/2013
1	Adrenal Insufficiency (Adrenal Gland Hypofunction) 03/2008
1	Hyperbilirubinemia 05/2007
1	Pathologic Complete Response 04/2006
1	Ischemic Stroke 03/2005
1	Hemorrhage 03/2005

Drug/Important Bio-Agent (IBA)

19	Asparaginase (Elspar)FDA Link 01/2022 - 10/2005
7	pegaspargase (Oncaspar)FDA Link 03/2022 - 01/2006
5	Prednisone (Sone)FDA LinkGeneric 02/2016 - 07/2002
4	Imatinib Mesylate (Gleevec)FDA Link 01/2021 - 02/2009
3	AntibodiesIBA 03/2022 - 01/2011
3	blinatumomabIBA 01/2022 - 12/2016
3	SteroidsIBA 01/2022 - 05/2007
3	nilotinib FDA Link 01/2021 - 12/2019
3	Pharmaceutical PreparationsIBA 01/2020 - 07/2013
3	Biological ProductsIBA 11/2019 - 03/2005
3	AsparagineIBA 01/2019 - 11/2013
2	Immunoglobulins (Immunoglobulin)IBA 05/2022 - 01/2016
2	Dasatinib (BMS 354825)FDA Link 01/2021 - 07/2013
2	BilirubinIBA 01/2021 - 01/2020
2	Dexamethasone (Maxidex)FDA LinkGeneric 01/2020 - 03/2008
2	Therapeutic UsesIBA 03/2014 - 03/2013
2	Methotrexate (Mexate)FDA LinkGeneric 10/2013 - 05/2007
2	DNA (Deoxyribonucleic Acid)IBA 01/2008 - 09/2005
1	T-Cell Antigen Receptors (T-Cell Receptor)IBA 05/2022
1	Polyethylene Glycols (Polyethylene Glycol)FDA LinkGeneric 03/2022
1	Immunoglobulin G (IgG)IBA 01/2022
1	CalicheamicinsIBA 01/2022
1	Inotuzumab OzogamicinIBA 01/2022
1	daratumumabIBA 01/2022
1	TransferasesIBA 01/2021
1	Alanine (L-Alanine)FDA Link 01/2021
1	EmapalumabIBA 01/2020
1	InterferonsIBA 01/2020
1	SmokeIBA 01/2020
1	Tyrosine Kinase InhibitorsIBA 12/2019
1	Oseltamivir (Tamiflu)FDA Link 10/2019
1	CohesinsIBA 08/2019
1	A-factor (Streptomyces)IBA 01/2019
1	Fibrinogen (Factor I)FDA Link 01/2019
1	Neutralizing AntibodiesIBA 03/2016
1	Cytarabine (Cytosar-U)FDA LinkGeneric 02/2016
1	Mercaptopurine (6 Mercaptopurine)FDA LinkGeneric 02/2016
1	Cyclophosphamide (Cytoxan)FDA LinkGeneric 02/2016
1	Tumor Suppressor Protein p14ARF (p14ARF)IBA 01/2016
1	Cyclin-Dependent Kinase Inhibitor p16IBA 01/2016
1	SolventsIBA 12/2014
1	InsecticidesIBA 12/2014
1	Proteins (Proteins, Gene)FDA Link 12/2013
1	Platinum Compounds (Compounds, Platinum)IBA 10/2013
1	Antineoplastic Agents (Antineoplastics)IBA 10/2013
1	Core Binding Factors (Core-Binding Factor)IBA 07/2013
1	vinyltriethoxysilane (VTES)IBA 07/2013
1	Daunorubicin (Cerubidine)FDA LinkGeneric 02/2013
1	CGP 74588IBA 02/2009
1	Hydrocortisone (Cortisol)FDA LinkGeneric 03/2008
1	CytochromesIBA 05/2007
1	Glucuronosyltransferase (UDP Glucuronosyltransferase)IBA 05/2007
1	Calcitriol Receptors (Calcitriol Receptor)IBA 05/2007
1	Heparin (Liquaemin)FDA LinkGeneric 03/2005
1	Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA 03/2005
1	Glutathione Transferase (Glutathione S-Transferase)IBA 05/2003

Therapy/Procedure

19	Therapeutics 10/2020 - 09/2005
7	Drug Therapy (Chemotherapy) 01/2022 - 10/2005
2	Investigational Therapies (Experimental Therapy) 12/2020 - 07/2013
1	Consolidation Chemotherapy 01/2021
1	Remission Induction 01/2011
1	Berlin-Frankfurt-Muenster protocol II 07/2002